Endocrine Abstracts

A 20-year-old man presented to his general practitioner in 1990 with 4-months history of general malaise. He was clinically and biochemically thyrotoxic. Carbimazole was started but the patient stopped treatment on his own after 2 months. Two years later he was referred to our department with severe thyrotoxicosis marked by lethargy, shaking, palpitations and weight loss (FT4 116.6 pmol/l (reference range 10–24.5 pmol/l) TT3 8.8 nmol/l (1.0–2.5 ...

Introduction: Vitamin D deficiency is increasingly being recognized as a widely prevalent metabolic disorder in temperate climates with various systemic manifestations. However topical, it is important to exclude tumour induced osteogenic osteomalacia as a possible aetiology in severe vitamin D deficiency when other risk factors (vegetarian diet, ethnicity, etc.) are absent. Early diagnosis of malignant tumours could be life saving and their resection may make this vitamin D r...